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Risk factors for the development of atherosclerosis in childhood and adolescence. Cardiovascular diseases CVD are a major cause of death in developed countries as well as in developing countries. In general, the clinical manifestations of CVD, such as myocardial infarction, stroke and peripheral vascular disease, are caused by an atherosclerotic process with onset as from the middle age. However, current studies indicate that the atherosclerotic process starts to develop in childhood.

The pathogenesis of atherosclerosis has been studied as to its inflammatory aspect. Among the inflammatory Floripondio droga yahoo dating, C-reactive protein CRP has been extensively studied in individuals with CVD, including those apparently healthy. High CRP levels have been related to risk factors for atherosclerosis: A great part of these risk factors may be influenced by lifestyle modifications, such "Floripondio droga yahoo dating" changes in eating habits and engagement in physical activities.

The effects of physical activity on CRP levels in adulthood are documented in the literature, however little is known on the influence of an active or sedentary lifestyle of children and adolescents on CRP levels.

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Thus, the objective of this study is to review the impact of physical activity of children and adolescents on CRP levels and the risk factors for the development of CVD. Coronary arteriosclerosis; motor Floripondio droga yahoo dating child; adolescent. Cardiovascular diseases CVD are a major cause of death in developed countries as well as in developing countries 1.

In general, the clinical manifestations of CVD start in the middle age. However, recent studies indicate that the atherosclerotic process starts to develop in childhood.

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Fatty streaks precursor of atherosclerotic plaques appear in the aortic intima at three years of age, and in the coronary arteries during adolescence 2. Thus, atherosclerosis gradually changed from a model of a chronic degenerative disease exclusively affecting patients with advanced age to a model of a subclinical chronic inflammatory disease already existing in childhood 3.

CRP has been a widely used inflammatory marker for the detection of CVD because its plasma concentration is easy to determine and it has the best clinical and epidemiological correlation to date. High blood CRP levels have been found in inflamed tissues, atherosclerotic vessels and infarcted myocardium 5.

Its utilization has been important for the possibility of identifying new pathways for the prevention and treatment of CVD and of risk factors for atherosclerosis 4,6: A great part of these factors may be influenced by lifestyle changes, thus reducing cardiovascular events and increasing the individuals' life expectancy. Modifications in eating habits and practice of physical activities are lifestyle changes that may significantly diminish risk factors for CVD and reduce CRP 6. The strategies for CRP reduction were initially based on pharmacological treatments 4,7.

Although these studies prove the positive effect of these therapies on CRP reduction in adults, little is known of the effect of physical activity on CRP in childhood and adolescence. The demonstration that cardiovascular diseases may originate Floripondio droga yahoo dating childhood and adolescence leads to the need that these risk factors be extensively investigated in these phases, with the purpose of planning increasingly earlier and possibly finding more effective interventions on these factors, thus further reducing morbidity and mortality.

The pathophysiology of CVD, the major causes of morbidity and mortality worldwide, starts at Floripondio droga yahoo dating early age. CVD are part of the group of chronic non-communicable diseases that comprise the plurimetabolic syndrome obesity, hypertension, diabetes mellitus and dyslipidemia caused by risk factors resulting from changes "Floripondio droga yahoo dating" lifestyle habits 8. The likelihood of occurrence of CVD increases in the presence of multiple risk factors established for atherosclerosis.

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